A gamble, when queasy, drinking tiniest bit of lemon squash, say (4,4)
I believe the answer is:
ball game
'squash say' is the definition.
'a gamble when queasy drinking tiniest bit of lemon' is the wordplay.
'when queasy' indicates anagramming the letters.
'drinking' indicates putting letters inside.
'tiniest bit of' suggests taking the first letters.
The initial letter of 'lemon' is 'l'.
'a'+'gamble'='agamble'
'agamble' is an anagram of 'balgame'.
'balgame' going around 'l' is 'BALL GAME'.
(Other definitions for ball game that I've seen before include "soccer, for example" , "rugby, perhaps" , "A sport such as soccer, rugby, cricket, hockey etc" , "Tennis or hurling, for example" , "Eg, tennis or rugby" .)