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A giant so upset in South American capital (8)

Ross

I believe the answer is:

santiago

'south american capital' is the definition.
(capital of Chile)

'a giant so upset' is the wordplay.
'upset' indicates an anagram.
'a'+'giant'+'so'='agiantso'
'agiantso' anagrammed gives 'SANTIAGO'.

'in' acts as a link.

(Other definitions for santiago that I've seen before include "City" , "Capital of Chile" , "Chilean capital" , "Chile's capital" , "South American capital" .)

I've seen this clue in the Sydney Morning Herald.
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