A great book but may be all Greek to readers (7)
I believe the answer is:
classic
'a great book' is the definition.
'classic' can be an answer for 'book' (thesaurus). I am unsure of the 'a great' bit.
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for classic that I've seen before include "Race, eg Derby" , "Very great work of art" , "First-class" , "Major long-standing sporting event" , "big race" .)