A loose relation (6)
I believe the answer is:
auntie
'relation' is the definition.
(auntie is a kind of relation)
'a loose' is the wordplay.
'loose' becomes 'untie' (I've seen this before).
'a'+'untie'='AUNTIE'
(Other definitions for auntie that I've seen before include "Female relative" , "BBC; relative (colloq,)" , "Relation; the BBC" , "Relative (familiar)" , "Family relative" .)