A loose woman in the family (6)
I believe the answer is:
auntie
'woman in the family' is the definition.
(I've seen this before)
'a loose' is the wordplay.
'loose' becomes 'untie' (loose can mean to untie or unleash).
'a'+'untie'='AUNTIE'
(Other definitions for auntie that I've seen before include "Close relative" , "The Beeb" , "Relative (familiar)" , "Female relative" , "Female relation" .)