A murderer is able to get out of line (4)
I believe the answer is:
cain
'a murderer' is the definition.
(Cain who killed Abel)
'able to get out of line' is the wordplay.
'able' becomes 'can'.
'to get' means one lot of letters goes inside another.
'out of line' becomes 'i' (I can't justify this - if you can you should believe this answer much more).
'can' enclosing 'i' is 'CAIN'.
'is' is the link.
Can you help me to learn more?
(Other definitions for cain that I've seen before include "Brother of Abel" , "Adam's son" , "First person born in Bible" , "The first known murderer" , "Eve's firstborn" .)