A nationalist manoeuvre involving Republican on American continent (10)
I believe the answer is:
antarctica
'continent' is the definition.
(I know that Antarctica is a continent)
'a nationalist manoeuvre involving republican on american' is the wordplay.
I cannot really see how this works, but
'a' could be 'an' and 'an' is found within the answer.
'republican' could be 'r' (abbreviation) and 'r' is found within the answer.
'manoeuvre' could be 'tactic' (synonyms) and 'tactic' is found in the leftover letters.
'american' could be 'a' (common abbreviation - e.g. in organisation names) and 'a' is found in the answer.
No letters remain.
This explanation may well be incorrect...
(Other definitions for antarctica that I've seen before include "Southern polar region" , "South polar region" , "cold place" , "continent" .)