A nice turn in variety? Not sure (9)
I believe the answer is:
uncertain
'not sure' is the definition.
('uncertain' is the opposite to 'sure')
'a nice turn in variety?' is the wordplay.
'in variety?' indicates anagramming the letters (I've seen 'in variety' mean this (I've seen this in other clues)).
'a'+'nice'+'turn'='aniceturn'
'aniceturn' is an anagram of 'UNCERTAIN'.
(Other definitions for uncertain that I've seen before include "Not definitely known" , "Unsure" , "Not convinced" , "up in the air" , "Not completely confident or sure of" .)