A number of misguided leavers (7)
I believe the answer is:
several
'a number of' is the definition.
(I've seen this in another clue)
'misguided leavers' is the wordplay.
'misguided' is an anagram indicator (I've seen this in other clues).
'leavers' is an anagram of 'SEVERAL'.
(Other definitions for several that I've seen before include "A good few" , "Some participants" , "Sundry, distinct" , "A few; separate" , "Assorted" .)