A pop singer may well take him in hand (4)
I believe the answer is:
mike
'him in hand' is the definition.
'Mike' can be an answer for 'him'. I am unsure of the 'in hand' bit.
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for mike that I've seen before include "letter in code" , "may need this to speak" , "T [Thespian] Reid" , "Sound receiver" , "comes before November" .)