A pram manufacturing city (5)
I believe the answer is:
parma
'city' is the definition.
(I have seen 'Italian city' mean 'parma' so perhaps 'city' could also mean 'parma')
'a pram manufacturing' is the wordplay.
'manufacturing' indicates anagramming the letters.
'a'+'pram'='apram'
'apram' is an anagram of 'PARMA'.
(Other definitions for parma that I've seen before include "Italian city famous for cheese and ham" , "Italian city known for ham and violets" , "Here in Italy" , "It. ham city; its Charterhouse, Stendhal" , "Source of ham and cheese" .)