A shrew yours truly is about to take in hand (6)
I believe the answer is:
manage
'take in hand' is the definition.
The answer and definition can be both to do with social activities as well as being verbs in their base form.
Perhaps there's an association between them I don't understand?
'a shrew yours truly is about' is the wordplay.
'shrew' becomes 'nag' (shrew can mean a nagging woman).
'yours truly' becomes 'me' (the person who set this crossword).
'is about' indicates putting letters inside.
'a'+'nag'='anag'
'anag' put inside 'me' is 'MANAGE'.
'to' is the link.
Can you help me to learn more?
(Other definitions for manage that I've seen before include "get on" , "Run, administer" , "Run (a football team)" , "Run; cope" , "Be in overall control of" .)