A smile's turned out to be random (7)
I believe the answer is:
aimless
'to be random' is the definition.
(I've seen this in another clue)
'a smile's turned' is the wordplay.
'turned' is an anagram indicator.
'smiles' is an anagram of 'imless'.
'a'+'imless'='AIMLESS'
'out' is the link.
(Other definitions for aimless that I've seen before include "Lacking a goal" , "lacking direction" , "Without purpose or direction" , "Without purpose or plan" , "With no plan or programme" .)