A squashed gnat could spoil the flavour (4)
I believe the answer is:
tang
'the flavour' is the definition.
(synonyms)
'a squashed gnat could spoil' is the wordplay.
'gnat' anagrams to 'TANG'.
However, I am unsure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for tang that I've seen before include "Old dynasty" , "Bitter aftertaste - prong" , "Thrash with good" , "Strong, pungent taste" , "characteristic quality" .)