A substance that can invigorate and rile up touring team (6)
I believe the answer is:
elixir
'a substance that can invigorate' is the definition.
(magical potion supposedly giving eternal life)
'rile up touring team' is the wordplay.
'up' is a reversal indicator (in down clue: letters go upwards).
'touring' means one lot of letters goes inside another (touring can mean going round).
'team' becomes 'xi' (eleven, a football team).
'rile' reversed gives 'elir'.
'elir' placed around 'xi' is 'ELIXIR'.
'and' is the link.
(Other definitions for elixir that I've seen before include "Cure-all potion" , "Medicinal solution" , "The one of life was sought by alchemists" , "Magic cure-all" , "Powerful potion" .)