A sweep makes little money in Ghana (6)
I believe the answer is:
pesewa
'money in ghana' is the definition.
'pesewa' can be an answer for 'money' (I have seen 'Ghanaian money ' mean 'pesewa' so perhaps 'money' could also mean 'pesewa'). I'm unsure of the 'in ghana' bit.
'a sweep makes little' is the wordplay.
'makes' indicates an anagram.
'little' becomes 'a' (I can't explain this - if you can you should give a lot more credence to this answer).
'sweep' anagrammed gives 'pesew'.
'pesew'+'a'='PESEWA'
Can you help me to learn more?
(Other definitions for pesewa that I've seen before include "Ghanaian monetary unit" , "Ghanaian money" , "Money in Africa" .)