A throw of the dice rejected in centre of revolution (4)
I believe the answer is:
axis
'centre of revolution' is the definition.
(eg a planet revolves around its axis)
'a throw of the dice rejected' is the wordplay.
'throw of the dice' becomes 'six' (potential result on a standard six-sided die).
'rejected' is a reversal indicator.
'six' in reverse letter order is 'xis'.
'a'+'xis'='AXIS'
'in' acts as a link.
(Other definitions for axis that I've seen before include "vertebra" , "all revolves around this" , "from Germany and Italy, originally" , "line to be turned round" , "Imaginary line about which a body rotates and a Dublin theatre" .)