A US city, no matter which (3)
I believe the answer is:
any
'no matter which' is the definition.
(I've seen this before)
'a us city' is the wordplay.
'us city' becomes 'ny' (I've seen this in other clues**).
'a'+'ny'='ANY'
(Other definitions for any that I've seen before include "Several" , "A lot < ? Not a lot < -- some" , "Some; none in particular" , "At all; in some degree" , "'Whatever'" .)