A woman in dire extremes in booze (5)
I believe the answer is:
adele
'a woman' is the definition.
'dire extremes in booze' is the wordplay.
'extremes' says to hollow out the word (remove centre letters).
'in' is an insertion indicator.
'booze' becomes 'ale' (type of alcohol).
'dire' with its centre removed is 'de'.
'de' inserted within 'ale' is 'ADELE'.
'in' acts as a link.
(Other definitions for adele that I've seen before include "girl" , "Singer with albums titled 19, 21 and 25" , "Popular female singer" , "Female singer from London" , "Performer" .)