A wretched cold (9)
I believe the answer is:
apathetic
'cold' is the definition.
(thesaurus)
'a wretched' is the wordplay.
'wretched' becomes 'pathetic' ('pathetic' can be a synonym of 'wretched').
'a'+'pathetic'='APATHETIC'
(Other definitions for apathetic that I've seen before include "Having little interest, indifferent" , "Showing no emotion or interest" , "disinclined to act" , "Impassive" , "Indifferent - without emotion" .)