Abandon in wilderness (6)
I believe the answer is:
desert
This clue is a double definition.
'abandon' is the first definition.
('desert' can be a synonym of 'abandon')
'wilderness' is the second definition.
(thesaurus)
'in' acts as a link.
(Other definitions for desert that I've seen before include "Waterless area of land" , "Sweet" , "See 33 Down" , "Walk out on" , "Leave - due" .)