Abandoned lads out of hand, many times over (1,12)
I believe the answer is:
a thousandfold
'many times over' is the definition.
I don't know anything about this answer so I cannot judge whether this works.
'abandoned lads out of hand' is the wordplay.
'abandoned' indicates anagramming the letters (the original order is abandoned).
'lads'+'out'+'of'+'hand'='ladsoutofhand'
'ladsoutofhand' anagrammed gives 'A THOUSANDFOLD'.
Can you help me to learn more?
(Another definition for a thousandfold that I've seen is " masses?".)