About a quarrel with despicable individual (7)
I believe the answer is:
caitiff
'individual' is the definition.
(caitiff is a kind of individual)
'about a quarrel with despicable' is the wordplay.
'about' indicates putting letters inside.
'quarrel' becomes 'tiff' (informal term for an argument).
'with' says to put letters next to each other.
'despicable' becomes 'ci' (I am not sure about this - if you are sure you should believe this answer much more).
'tiff' after 'ci' is 'citiff'.
'a' put into 'citiff' is 'CAITIFF'.
Can you help me to learn more?
(Other definitions for caitiff that I've seen before include "Cur" , "Base" , "Despicable fellow" .)