About to enter a wild no-go area of America (6)
I believe the answer is:
oregon
'area of america' is the definition.
(I've seen this before)
'about to enter a wild no-go' is the wordplay.
'about' becomes 're' (regarding).
'to enter' indicates putting letters inside.
'a wild' indicates an anagram.
'no'+'go'='nogo'
'nogo' with letters rearranged gives 'ogon'.
're' inserted inside 'ogon' is 'OREGON'.
(Other definitions for oregon that I've seen before include "US state, capital Salem" , "US west-coast state" , "W. coast US state" , "area of America" , "US NW coastal state" .)