Abuse some pharmaceuticals (4)
I believe the answer is:
harm
'abuse' is the definition.
(thesaurus)
'some pharmaceuticals' is the wordplay.
'some' indicates a hidden word (some of the parts of the word are used).
'HARM' is hidden in the letters of 'pharmaceuticals'.
(Other definitions for harm that I've seen before include "Hurt, injure" , "Hurt, maim" , "Injure or damage" , "Short-long metric feet" , "Injure, injury" .)