Accumulate a great amount (5)
I believe the answer is:
amass
'accumulate' is the definition.
(synonyms)
'a great amount' is the wordplay.
'great amount' becomes 'mass'.
'a'+'mass'='AMASS'
(Other definitions for amass that I've seen before include "Collect or gather" , "Sodium chloride" , "Gathers" , "Stock up on" , "store" .)