Accuse snow leopard on the retreat (8)
I believe the answer is:
denounce
'accuse' is the definition.
(I've seen this in another clue)
'snow leopard on the retreat' is the wordplay.
'snow leopard' becomes 'ounce' (ounce is an alternative name for the snow leopard).
'on' means one lot of letters go next to another.
'the retreat' becomes 'den' (both can mean a lair or hideout).
'ounce' after 'den' is 'DENOUNCE'.
(Other definitions for denounce that I've seen before include "Hit out at" , "Inform against (someone)" , "Criticise or condemn" , "Speak publicly or give information against" , "Condemn or censure" .)