Accustomed to Edward following us (4)
I believe the answer is:
used
'accustomed' is the definition.
(I've seen this in another clue)
'edward following us' is the wordplay.
'edward' becomes 'Ed' (short for Edward).
'following' is a charade indicator (letters next to each other).
'ed' put after 'us' is 'USED'.
'to' acts as a link.
(Other definitions for used that I've seen before include "Second-hand; consumed" , "with a previous owner" , "worked unfairly" , "Employed - exploited" , "Sued, having been employed" .)