Ache with cold during Asiatic storm (8)
I believe the answer is:
sciatica
'ache' is the definition.
(I know that sciatica is a type of neuralgia)
'cold during asiatic storm' is the wordplay.
'cold' becomes 'c' (eg on taps).
'during' is an insertion indicator.
'storm' indicates an anagram.
'asiatic' anagrammed gives 'sciatia'.
'c' inserted inside 'sciatia' is 'SCIATICA'.
'with' acts as a link.
(Other definitions for sciatica that I've seen before include "Form of neuralgia" , "Neuralgia of the hip and thigh" , "Type of neuritis" , "Intense pain in the leg" , "I cast CIA out for this painful disorder" .)