Active enough to chuck the doctor in the river! (6)
I believe the answer is:
nimble
'active' is the definition.
(similar in meaning)
'doctor in the river' is the wordplay.
'doctor' becomes 'MB' (Bachelor of Medicine, Medicinae Baccalaureus).
'in the' indicates putting letters inside.
'river' becomes 'nile' (Nile River is an example).
'mb' going into 'nile' is 'NIMBLE'.
'enough to chuck the' acts as a link.
This may not be right. Some or all of it may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for nimble that I've seen before include "Quick, agile" , "Agile - alert" , "'Agile, spry (6)'" , "Quick on the feet" , "Fast; light in movement" .)