Actor Brian sanctified (7)
I believe the answer is:
blessed
'sanctified' is the definition.
('bless' can be a synonym of 'sanctify')
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for blessed that I've seen before include "Endowed" , "Highly favoured or fortunate" , "in heaven" , "Bedless (anag.)" , "darned" .)