Acts up without us in agreement (4)
I believe the answer is:
pact
'agreement' is the definition.
(pact is a kind of agreement)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for pact that I've seen before include "Written agreement between two states" , "Treaty, formal agreement" , "'Accord, treaty (4)'" , "Agreement, bargain" , "Alliance" .)