Admittedly bound to change (2,5)
I believe the answer is:
no doubt
'admittedly' is the definition.
(thesaurus)
'bound to change' is the wordplay.
'change' indicates an anagram.
'bound'+'to'='boundto'
'boundto' with letters rearranged gives 'NO DOUBT'.
(Other definitions for no doubt that I've seen before include "Almost certainly" , "To be sure" , "Bound to, unquestionably" , "sign of agreement" , "Surely" .)