African's guide dog every so often left with large toy (3,4)
I believe the answer is:
rag doll
'toy' is the definition.
(rag doll is a kind of toy)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for rag doll that I've seen before include "plaything's required" , "Page 3 cutie?" , "Child's toy" , "suitable gift for little girl" , "Page three girl" .)