After a day and a quarter, some leave (6)
I believe the answer is:
depart
'leave' is the definition.
(I know that leave can be written as depart)
'after a day and a quarter some' is the wordplay.
'after' is a charade indicator (letters next to each other).
'a day' becomes 'd' (abbreviation for day).
'and' means one lot of letters go next to another.
'a quarter' becomes 'e'.
'some' becomes 'part' (only part of something).
'd'+'e'='de'
'de' put next to 'part' is 'DEPART'.
(Other definitions for depart that I've seen before include "Quit" , "Clearly expressive" , "Set out" , "make tracks" , "Go away or leave" .)