Again, having recovered from the effects of (4)
I believe the answer is:
over
'again' is the definition.
(as in the phrases 'start over' and 'start again')
'recovered from the effects of' is the wordplay.
'OVER' is hidden within the letters.
But, I am unsure how this is indicated.
'having' acts as a link.
Can you help me to learn more?
(Other definitions for over that I've seen before include "Rouond of six bowls in cricket" , "Completely ended" , "Finished -- as a remainder" , "superior position" , "Concerning" .)