Again, rhyme with "defeat" (7)
I believe the answer is:
reverse
'defeat' is the definition.
(I've seen this before)
'again rhyme' is the wordplay.
'again' becomes 're'.
'rhyme' becomes 'verse' ('verse' can be a synonym of 'rhyme').
're'+'verse'='REVERSE'
'with' acts as a link.
(Other definitions for reverse that I've seen before include "Upset" , "Tails (of a coin)" , "Turn inside out or upside down" , "Countermand" , "Move backwards" .)