Agency, largely understanding manufacturing needs, arranges openings for graduate (6)
I believe the answer is:
alumna
'graduate' is the definition.
(synonyms)
'agency largely understanding manufacturing needs arranges openings' is the wordplay.
'openings' says to take the initial letters (I've seen 'opening' mean this).
The first letters of 'agency largely understanding manufacturing needs arranges' is 'ALUMNA'.
'for' is the link.
(Other definitions for alumna that I've seen before include "Female graduate" , "Female former pupil" , "She studied" , "Harvard graduate" , "Manual (anag) - old girl" .)