Agenda revolutionary Law Lord set up in Home Counties (8)
I believe the answer is:
schedule
'agenda' is the definition.
(synonyms)
'revolutionary law lord set up in home counties' is the wordplay.
'revolutionary' becomes 'che' (Che Guevara the Marxist revolutionary).
'law lord' becomes 'lud' (I've seen this in other clues).
'set up' shows that the letters should be reversed in order.
'in' means one lot of letters goes inside another.
'home counties' becomes 'se' (Home Counties in the South East of England).
'lud' back-to-front is 'dul'.
'che'+'dul'='chedul'
'chedul' inserted within 'se' is 'SCHEDULE'.
(Other definitions for schedule that I've seen before include "Timetable; plan of action" , "Agenda" , "Clues he'd dropped about timetable" , "Inventory - programme" , "Rota" .)