Agitated confederates lose their reason and turn traitor? (6)
I believe the answer is:
defect
'turn traitor?' is the definition.
(thesaurus)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for defect that I've seen before include "go over to the other side" , "Lack" , "Flaw; turn traitor" , "Transfer allegiance to opposition" , "Shortcoming" .)