Agree with boss to go after desktop when nobody's around (3,4,4)

'agree' is the definition.
(nodding indicates agreement)

'boss to go after desktop when nobody's around' is the wordplay.
I cannot really understand how this works, but
'boss' could be 'head' (synonyms) and 'head' is found within the answer.
'go' could be 'do' (doing is a kind of going) and 'do' is located in the answer.
'when' could be 'on' (I've seen this in other clues) and 'on' is located in the answer.
This may be the basis of clue (or it may be nonsense).

'with' is the link.