Crossword Genius

Agreement number five hundred (3)

Ross

I believe the answer is:

nod

'agreement' is the definition.
(a nod indicates agreement)

'number five hundred' is the wordplay.
'number' becomes 'no' (abbreviation).
'five hundred' becomes 'd' (Roman numeral for 500).
'no'+'d'='NOD'

(Other definitions for nod that I've seen before include "Gesture of agreement" , "sign of approval" , "Signal with the head" , "sleepy land" , "Drop the head" .)

I've seen this clue in the Evening Standard.
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