Aim a pistol originally confiscated by father (6)
I believe the answer is:
aspire
'aim' is the definition.
(I know that aim can be written as aspire)
'a pistol originally confiscated by father' is the wordplay.
'originally' indicates taking the first letters.
'confiscated by' indicates putting letters inside.
'father' becomes 'sire' (synonyms).
The first letter of 'pistol' is 'p'.
'p' put into 'sire' is 'spire'.
'a'+'spire'='ASPIRE'
(Other definitions for aspire that I've seen before include "I spare (anag.)" , "Have aspiration for, aim at" , "Earnestly desire (to achieve something)" , "Yearn, dream (towards)" , "Have a strong desire to reach an objective" .)