Aim when facing pressure and anger (6)
I believe the answer is:
aspire
'aim' is the definition.
('aspire' can be a synonym of 'aim')
'when facing pressure and anger' is the wordplay.
'when' becomes 'as'.
'facing' says to put letters next to each other.
'pressure' becomes 'p' (abbreviation).
'and' is a charade indicator (letters next to each other).
'anger' becomes 'ire' ('ire' can be a synonym of 'anger').
'as'+'p'+'ire'='ASPIRE'
(Other definitions for aspire that I've seen before include "Have lofty aims" , "Aim, have an ambitious plan" , "Persia (anag.)" , "rise to a great height" , "Aim, shoot for" .)