Alcohol clergy bottled at home (8)
I believe the answer is:
'alcohol' is the definition.
(I know that glycerin is a type of alcohol)
'clergy bottled at home' is the wordplay.
'bottled' indicates anagramming the letters (bottled can mean drunk).
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'clergy' with letters rearranged gives 'glycer'.
(Other definitions for glycerin that I've seen before include "Sweet-tasting viscous fluid" , "Sweet and viscous liquid (US spelling)" .)