Alienated, disaffected (9)
I believe the answer is:
estranged
This clue is a double definition.
'alienated' is the first definition.
(I know that alienated can be written as estranged)
'disaffected' is the second definition.
('estrange' can be a synonym of 'disaffect')
(Other definitions for estranged that I've seen before include "Having become unfriendly or alienated" , "Alienated, disaffected" , "no longer friendly" , "Cut off" , "Sad regent (anag) - disaffected" .)