All are affected by English beer (4,3)
I believe the answer is:
real ale
'beer' is the definition.
(type of beer)
'all are affected by english' is the wordplay.
'affected' indicates anagramming the letters.
'by' is a charade indicator (letters next to each other).
'english' becomes 'e' (abbreviation).
'all'+'are'='allare'
'allare' anagrammed gives 'realal'.
'realal'+'e'='REAL ALE'
(Other definitions for real ale that I've seen before include "Traditional drink" , "Traditional beer" , "Beer fermented in cask, served without carbon dioxide" , "What CAMRA wants" , "CAMRA interest" .)