American following Republican account - one doing spin about 50 states (6)
I believe the answer is:
africa
'about 50 states' is the definition.
(Africa is made up of around 50 countries)
'american following republican account one doing spin' is the wordplay.
'american following republican' becomes 'afr' (this could be a standard abbreviation which I don't know about).
'account' becomes 'ac' (abbreviation for account).
'one' becomes 'I' (Roman numeral).
'doing spin' is a reversal indicator (letters spin around).
'ac'+'i'='aci'
'aci' reversed gives 'ica'.
'afr'+'ica'='AFRICA'
(Other definitions for africa that I've seen before include "Second-largest continent" , "Always something new from it (Pliny)" , "Large land mass" , "Second largest continent" , "Location of 14 downb" .)