American information on following sick fantasy (8)
I believe the answer is:
illusion
'fantasy' is the definition.
(I know that fantasy can be written as illusion)
'american information on following sick' is the wordplay.
'american' becomes 'US' (United States).
'information' becomes 'i' (common abbreviation for information).
'following' says to put letters next to each other.
'sick' becomes 'ill' (similar in meaning).
'us'+'i'+'on'='usion'
'usion' put after 'ill' is 'ILLUSION'.
(Other definitions for illusion that I've seen before include "False idea or conjuring trick" , "can you believe it?" , "Wrong belief or fancy, may be optical" , "Magic trick" , "False belief or image, like mirage" .)