Crossword Genius

American uncle plays a major part (3)

Ross

I believe the answer is:

sam

'american uncle' is the definition.
(Uncle Sam is a nickname for the USA)

'plays a major part' is the wordplay.
'part' indicates a hidden word.
'SAM' is hidden in the letters of 'plays a major'.

(Other definitions for sam that I've seen before include "together once" , "Boy" , "Uncle" , "Casablanca piano player" .)

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